Product name: AMG 232
Chemical name: 2-((3R,5R,6S)-5-(3-chl or ophenyl)-6-(4-chl or ophenyl)-1-((S)-1-(is opropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acidWeb Site click
MF: C28H35Cl2NO5S
MW: 568.55
C AS NO: 75706-12-6 Product: Leflunomide
Purity: 100%
Soluble: Soluble in DMSOHMG-CoA Reduct ASe (HMGCR) Inhibitor s
Description: potent ,selective , and or ally bioav ailableMDM2-p53 Inhibitor (IC50value9.1nM,Kd0.045nM),demonstratingremarkablepharmacokineticproperties and invivoantitum or activity inthe SJSA-1osteosarcomaxenograftmodel.M or eover,AMG232activate sp53pathway activity invivo, and potent iatPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22330830
http://cathepsin-s.com
Cathepsins
