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Product name: ASK1 Inhibitor 10
Chemical name: N-(6-(1H-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl)-4-tert-butylbenzamide dihydrochlorideMedchemexpress
MF: C21H21N5O.2HCl
MW: 432.35
CAS NO: 2609-46-3 Product: Amiloride
Purity: 99%
Soluble: Soluble in DMSOGPR55 inhibitors
Description: Potent,selective,andorallybioavailableASK1inhibitor(IC50:14nM)withnoaffinityforarepresentativepanelofkinases(IC50:>10μM),exceptforASK2(IC50:0.51μM).Compound10showsahighligand-lipophilicityefficiency(LLE,pIC50–logD=4.69)value,whichavoidsissuesofundesirablePubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22312570

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Author: haoyuan2014