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Product name: AZ 20
Chemical name: (R)-4-(2-(1H-indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholineWeb Site:Medchemexpress
MF: C21H24N4O3S
MW: 412.51
CAS NO: 1227158-85-1 Product: BAY 87-2243
Purity: 99%
Soluble: Soluble in DMSONeurokinin Receptor inhibitors
Description: Potent,orallyactiveandselectiveinhibitorofATRproteinkinasewithmonotherapyinvivoantitumoractivity(IC50value5nM).AZ20potentlyinhibitsthegrowthofLoVocolorectaladenocarcinomatumorcellsinvitro,andisausefulcompoundtoexploreATRpharmacologyinvivo.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22313226

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Author: haoyuan2014