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Product name: AZD 2461
Chemical name: 4-(4-flu or o-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-oneWeb Site:Medchemexpress
MF: C22H22FN3O3
MW: 39543
C AS NO: 1233706-88-1 Product: CAY10650
Purity: 99%
Soluble: Soluble in DMSOHSV Inhibitor s
Description: PARP Inhibitor (IC50value5nM)with po or P-glyco proteinsubstratequalities.Unliketreatmentwith AZD2281(Olaparib,Axon1464),AZD2461succesfullycircumventsdrugresis tance of Pgp-pr of icienttum or s, and inactivation of p53-binding protein1(53BP1) AS acausalfac to rinPARPiresis tancePubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22323397

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