Product name: Amuvatinib- MP 470
Chemical name: N-(Benzo[d][1,3]dioxol-5-ylmethyl)-4-(benz ofuro[3,2-d]pyrimidin-4-yl)piperazine-1-carbothioamideWeb Site click
MF: C23H21N5O3S
MW: 44751
C AS NO: 1282512-48-4 Product: GDC-0032
Purity: 99%
Soluble: Soluble in DMSOR or Inhibitor s
Description: RTK Inhibitor which effectivelyinhibits PDGFR,c-Kit and c-Met(IC50 values lowµMrangeinvivo).Amuvatinibinfluencesvarioussurvival and DNArepairrelated proteinssuch AS pAKT,RAD51 and GSK-3β,inhibits cell proliferation, induces cell growtharrest and promotesapop to sis inpPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22331486
http://cathepsin-s.com
Cathepsins
