Product name: FRAX 486
Chemical name: 6-(2,4-dichl or ophenyl)-8-ethyl-2-(3-flu or o-4-(piperazin-1-yl)phenylamino)pyrido[2,3-d]pyrimidin-7(8H)-oneMedchemexpress
MF: C25H23Cl2FN6O
MW: 513.39
C AS NO: 26159-34-2 Product: Naproxen (sodium)
Purity: 99%
Soluble: Soluble in DMSOR or Inhibitor s
Description: bioav ailable and brainpenetrating Inhibitor of groupIp21-activate d kin ASe s(IC50 values 8.25nM,39.5nM, and 55.3nMf or PAK1,PAK2, and PAK3,respectively)with goodselectivityoverPAK4(IC50value779nM)FRAX486rescuesthe dendriticspineabn or mality and audiogenicseizures, and reduce sauPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22317756
http://cathepsin-s.com
Cathepsins
