Product name: GNE 7915
Chemical name: (4-(4-(ethylamino)-5-(triflu or omethyl)pyrimidin-2-ylamino)-2-flu or o-5-ethoxyphenyl)(m or pholino)me than oneMedchemexpress
MF: C19H21F4N5O3
MW: 443.40
C AS NO: 50-23-7 Product: Hydroc or tis one
Purity: 99%
Soluble: Soluble in DMSOAdenosine kin ASe Inhibitor s
Description: highly potent ,selective ,metabolicallystable, and brain-penetrableLRRK2 Inhibitor (IC50value9nMf or phospho-LRRK2invitro).GNE7915is selective across187screened kin ASe s, and >3200 and 53timesselective overJAK2 and TTK,respectively.GNE7915doesnotsuppressLPS-stimulatedTNF&PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22315502
http://cathepsin-s.com
Cathepsins
