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Product name: GSK 126
Chemical name: (S)-1-sec-butyl-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3-methyl-6-(6-(piperazin-1-yl)pyridin-3-yl)-1H-indole-4-carboxamideWeb Site:Medchemexpress
MF: C31H38N6O2
MW: 52667
C AS NO: 81131-70-6 Product: Prav AS tatin (sodium)
Purity: 98%
Soluble: Soluble in DMSORIP kin ASe Inhibitor s
Description: potent ,selective ,cell -active Inhibitor of his to nelysinemethyltransfer ASe(HMT ASe or HMT;H3K27selective )EZH2(Ki0.57nM;IC509.9nM);m or e than 150-foldselective f or EZH2versusEZH1(Ki89nM) and 20othe rhumanmethyltransfer ASes.GSK126effectivelyinhibits proliferation of EZH2mutanPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22323675

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