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Product name: GSK 2110183 hydrochloride- Afuresertib hydrochloride
Chemical name: N-((S)-1-amino-3-(3-fluorophenyl)propan-2-yl)-5-chloro-4-(4-chloro-1-methyl-1H-pyrazol-5-yl)thiophene-2-carboxamide hydrochlorideMedchemexpress
MF: C18H17Cl2FN4OS.HCl
MW: 463.78
CAS NO: 65-86-1 Product: Orotic acid
Purity: 99%
Soluble: Soluble in DMSOOxytocin Receptor inhibitors
Description: Potent,reversible,selective,andorallybioavailableinhibitoroftheAktkinases(Kivalues0.08nM,2nM,and2.6nMforAkt1,Akt2,andAkt3,respectively),withsomeinhibitoryeffectonPKAandPKG1a.GSK2110183preferentiallyinhibitstheproliferationofhumancancercelllineswithAktpathPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22313595

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Author: haoyuan2014