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Product name: IC 87114
Chemical name: 2-((6-amino-9H-purin-9-yl)methyl)-5-methyl-3-o- to lylquinazolin-4(3H)-oneMedchemexpress.com
MF: C22H19N7O
MW: 397.43
C AS NO: 153653-30-6 Product: D ofequidar (fumarate)
Purity: 98%
Soluble: Soluble in DMSOMembrane_Transp or ter/Ion_ channel _Compound_Library Inhibitor s
Description: potent and highly selective Small molecule Inhibitor of the PI3Kp110δis of or m(IC50 values f or PI3Kα,β,γ, and δare>100,75,29, and 0.5μMrespectively).IC87114potent lyinhibitedPIP3biosynthe sis inneutrophilsby 60–65% and at1μM,itinhibitedneutrophilmigrationby 75% AS comparedwith the coPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22321695

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