Product name: INCB 024360-analog- IDO inhibitor 5l
Chemical name: 4-amino-N-(3-chloro-4-fluorophenyl)-N-hydroxy-1,2,5-oxadiazole-3-carboximidamideWeb Site:Medchemexpress
MF: C9H7ClFN5O2
MW: 27164
CAS NO: 33286-22-5 Product: Diltiazem (hydrochloride)
Purity: 99%
Soluble: Soluble in DMSOHistone Methyltransferase inhibitors
Description: Potentcompetitiveinhibitorofindoleamine2,3-dioxygenase(IDO1,IC50value67nM)withinvivopharmacodynamicactivityandefficacyinamousemelanomamodel;ThisINCB024360-analogdecreasedkynureninelevelsby>50%inplasmaandinhibitedB16-GM-CSFtumorgrowthinadosedependentfasPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22311958
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Cathepsins