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Product name: LCS-1
Chemical name: 4,5-dichloro-2-m-tolylpyridazin-3(2H)-oneMedchemexpress
MF: C11H8Cl2N2O
MW: 255.10
CAS NO: 14976-57-9 Product: Clemastine (fumarate)
Purity: 99%
Soluble: Soluble in DMSOAdrenergic Receptor inhibitors
Description: Inhibitorofsuperoxidedismutase1(SOD1).InhibitsSOD1enzymaticactivityinvitro(IC50:0.19μMforcellgrowthinhibitioninKRASmutatedH358celllines).Conversely,(over-)expressionofSOD1cDNAshowedaboutathreefoldreductioninsensitivitytoLCS-1andincreasedproliferationofPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22312108

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Author: haoyuan2014