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Product name: LEE 011- Ribociclib
Chemical name: 7-cyclopentyl-N,N-dimethyl-2-(5-(piperazin-1-yl)pyridin-2-ylamino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamideWeb Site:Medchemexpress
MF: C23H30N8O
MW: 43454
C AS NO: 1211443-80-9 Product: LEE011 (hydrochl or ide)
Purity: 99%
Soluble: Soluble in DMSOSPHK Inhibitor s
Description: or ally bioav ailable and highly selective Small -molecule Inhibitor of CDK4/6(meanIC50value307nMinsensitiveneurobl AS to ma-derived cell lines).LEE011causedcell -cyclearrest and cell ularsene scence that w AS attributed to dose- dependent decre ASesinphosph or ylatedRB and FOXM1,respectiPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22314299

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Author: haoyuan2014