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Product name: PKI 587- PF 05212384
Chemical name: 1-(4-(4-(dimethylamino)piperidine-1-carbonyl)phenyl)-3-(4-(4,6-dim or pholino-1,3,5-triazin-2-yl)phenyl)ureaMedchemexpress
MF: C32H41N9O4
MW: 61573
C AS NO: 49671-76-3 Product: ZLN005
Purity: 99%
Soluble: Soluble in DMSONEDD8-activating Enzyme Inhibitor s
Description: highly potent PI3K/m to R kin ASe Inhibitor ;PKI-587inhibits PI3K-α,β,γ,δis of or ms and m to Rwith IC50 of 0.4,6.0,5.4,6.0 and 1.6nMrespectively.PKI-587inhibits m to R to C1 kin ASe activity inhumanMDA-MB-361cell s AS sessed AS surppression of 4EBP1phosph or ylationat References Certificates CatPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22316485

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Author: haoyuan2014