Product name: PLX 4032- RG 7204 | Vemurafenib | RO 5185426
Chemical name: N-(3-(5-(4-chl or ophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-diflu or ophenyl)propane-1-sulfonamideMedchemexpress
MF: C23H18ClF2N3O3S
MW: 489.92
C AS NO: 60-80-0 Product: Antipyrine
Purity: 98%
Soluble: Soluble in DMSOPTEN Inhibitor s
Description: selective Inhibitor of protein kin ASe , target ingB-Raf(V600E)(IC50:44nM);PLX4032h AS beenshown to causeprogrammedcell deathinmelanoma cell lines;apotent ialanti-tum or agentunderclinicaltrials References Certificates Categ or ies Extrain foGBollagetal.Clinicalefficacy of aRAFinhiPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22318712
http://cathepsin-s.com
Cathepsins