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Product name: R 547
Chemical name: (4-amino-2-(1-(methylsulfonyl)piperidin-4-ylamino)pyrimidin-5-yl)(2,3-diflu or o-6-methoxyphenyl)me than oneMedchemexpress
MF: C18H21F2N5O4S
MW: 44145
C AS NO: 40828-46-4 Product: Supr ofen
Purity: 99%
Soluble: Soluble in DMSOEGFR Inhibitor s
Description: potent and selective CDK Inhibitor with Ki values to be 1,3,1nMf or CDK1,CDK2, and CDK4respectively;inactive (Ki>5000nM) agains tapanel of >120unrelated kin ASe s.R547effectivelyinhibits proliferation of tum or cell linesin dependent o f multidrugresis tantstatus,his to logictype ,retinoblaPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22314514

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Author: haoyuan2014