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Product name: RO 4929097
Chemical name: (S)-2,2-dimethyl-N1-(6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)-N3-(2,2,3,3,3-pentaflu or opropyl)malonamideMedchemexpress
MF: C22H20F5N3O3
MW: 469.40
C AS NO: 60282-87-3 Product: Ges to dene
Purity: 98%
Soluble: Soluble in DMSOMNK Inhibitor s
Description: potent γ-secret ASe Inhibitor (GSI;IC50value4nM) target ingNotch Signalingwith invivoefficacyinvarioustum or cell s,showing>100-foldselectivitywith respect to 75othe r proteins of varioustype s(recep to rs,ion channel s, and enzymes).Treatmen to f HEK293cell swith RO4929097caPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22328412

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