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Product name: SirReal 2
Chemical name: 2-(4,6-dimethylpyrimidin-2-ylthio)-N-(5-(naphthalen-1-ylmethyl)thiazol-2-yl)acetamideWeb Site click
MF: C22H20N4OS2
MW: 420.55
C AS NO: 50-55-5 Product: Reserpine
Purity: 98%
Soluble: Soluble in DMSOGlucoc or ticoid Recep to r Inhibitor s
Description: SIRT2 Inhibitor (IC50value0.14µM)with invivo activity ,showing>1000foldselectivityoverothe rCl AS s-is irtuinsSIRT1 and SIRT3.Application of SirReal2leads to tubulinhyperacetylationinHeLacell s and induces destabilization of the checkpoint proteinBubR1.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22326559

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