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Product name: VE 822
Chemical name: 5-(4-(isopropylsulfonyl)phenyl)-3-(3-(4-((methylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amineMedchemexpress.com
MF: C24H25N5O3S
MW: 463.55
CAS NO: 749886-87-1 Product: JSH-23
Purity: 99%
Soluble: Soluble in DMSONeurotensin Receptor inhibitors
Description: SelectiveATRinhibitor(IC50values0.019µM,2.6µM,and18.1µMforATR,ATM,andDNA-PK,respectively)withinvitroandinvivoactivitythatdecreasesmaintenanceofcell-cyclecheckpointsandhomologousrecombinationinirradiatedcancercells,andincreasespersistentDNAdamage.VE822decrPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22313287

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Author: haoyuan2014