Product name: VX 745
Chemical name: 5-(2,6-dichl or ophenyl)-2-(2,4-diflu or ophenylthio)-6H-pyrimido[1,6-b]pyridazin-6-oneWeb Site click
MF: C19H9Cl2F2N3OS
MW: 436.26
C AS NO: 97-77-8 Product: Dis ulfiram
Purity: 99%
Soluble: Soluble in DMSOFatty Acid Synth ASe (F AS ) Inhibitor s
Description: highly potent and selective Inhibitor of p38αMAP kin ASe (IC50:10nM);being1000foldselective overcloselyrelated kin ASe s References Certificates Categ or ies Extrain foJPDuffyetal.the dis covery of VX-745:anovel and selective p38α kin ASe Inhibitor .ACSMed.Chem.Lett.2011,2,758.MCPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22316239
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Cathepsins