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Product name: WZ 4003
Chemical name: N-(3-(5-chl or o-2-(2-methoxy-4-(4-methylpiperazin-1-yl)phenylamino)pyrimidin-4-yloxy)phenyl)propionamideMedchemexpress
MF: C25H29ClN6O3
MW: 496.99
C AS NO: 1191385-19-9 Product: B-Raf Inhibitor 1 (dihydrochl or ide)
Purity: 99%
Soluble: Soluble in DMSOPGC-1(alpha) Inhibitor s
Description: Specificdual Inhibitor of NUAK1(akaARK5) and NUAK2(ak AS NARK;IC50 values 20nM and 100nM,respectively)with nosignificant Inhibitor yeffec to napanel of 139othe r kin ASe stested,includingtenothe rAMPK-related kin ASe s.WZ4003suppressedMYPT1phosph or ylationinadose- dependent manner,anPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22316571

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Author: haoyuan2014