E.; Manson, J.E.; Giovannucci, E.L.; Moorthy, M.V.; Zhang, S.; Lee, I.-M.; Lin, J.H. Circulating vitamin D levels and risk of colorectal cancer in women. Cancer Prev. Res. 2015, doi:10.1158/1940-6207.CAPR-14-0470. 37. Canto-Costa, M.H.; Kunii, I.; Hauache, O.M. Body fat and cholecalciferol supplementation in elderly homebound individuals. Braz. J. Med. Biol. Res. 2006, 39, 91?8. 38. Saadi, H.F.; Dawodu, A.; Afandi, B.O.; Zayed, R.; Benedict, S.; Nagelkerke, N. Efficacy of daily and monthly high-dose calciferol in vitamin d eficient nulliparous and lactating women. Am. J. Clin. Nutr. 2007, 85, 1565?571. 39. Harris, S.S.; Dawson-Hughes, B. Plasma vitamin D and 25OHD Necrostatin-1 manufacturer responses of young and old men to supplementation with vitamin D3. J. Am. Coll. Nutr. 2002, 21, 357?62. 40. Barger-Lux, M.J.; Heaney, R.P.; Dowell, S.; Chen, T.C.; Holick, M.F. Vitamin D and its major metabolites: Serum levels after graded oral dosing in healthy men. Osteoporos. Int. 1998, 8, 222?30. 41. Nelson, M.L.; Blum, J.M.; Hollis, B.W.; Rosen, C.; Sullivan, S.S. Supplements of 20 g/d cholecalciferol optimized serum 25-hydroxyvitamin D concentrations in 80 of premenopausal women in winter. J. Nutr. 2009, 139, 540?46. 42. Goussous, R.; Song, L.; Dallal, G.E.; Dawson-Hughes, B. Lack of effect of calcium intake on the 25-hydroxyvitamin D response to oral vitamin D3. Clin. Endocrinol. Metab. 2005, 90, 707?11. 43. Bacon, C.J.; Gamble, G.D.; Horne, A.M.; Scott, M.A.; Reid, I.R. High-dose oral vitamin D3 supplementation in the elderly. Osteoporos. Int. 2009, 20, 1407?415. 44. Trang, H.M.; Cole, D.E.C.; Rubin, L.A.; Pierratos, A.; Siu, S.; Vieth, R. Evidence that vitamin D3 increases serum 25-hydroxyvitamin D more efficiently than does vitamin D2. Am. J. Clin. Nutr. 1998, 68, 854?58. 45. Zwart, S.R.; Mehta, S.K.; Ploutz-Snyder, R.; Bourbeau, Y.; Locke, J.P.; Pierson, D.L.; Smith, S.M. Response to vitamin D supplementation during antarctic winter is related to bmi, and supplementation can mitigate epstein-barr virus reactivation. J. Nutr. 2011, 141, 692?97. 46. Waterhouse, M.; Tran, B.; Armstrong, B.K.; Baxter, C.; Ensartinib chemical information Ebeling, P.R.; English, D.R.; Gebski, V.; Hill, C.; Kimlin, M.G.; Lucas, R.M.; et al. Environmental, personal, and genetic determinants of response to vitamin D supplementation in older adults. J. Clin. Endocrinol. Metab. 2014, 99, E1332 1340.Nutrients 2015,47. Ng, K.; Scott, J.B.; Drake, B.F.; Chan, A.T.; Hollis, B.W.; Chandler, P.D.; Bennett, G.G.; Giovannucci, E.L.; Gonzalez-Suarez, E.; Meyerhardt, J.A.; et al. Dose response to vitamin D supplementation in african americans: Results of a 4-arm, randomized, placebo-controlled trial. Am. J. Clin. Nutr. 2014, 99, 587?98. 48. DeLappe, E.; McGreevy, C.; ni Chadhain, N.; Grimes, H.; O’Brien, T.; Mulkerrin, E. Vitamin D insufficiency in older female community-dwelling acute hospital admissions and the response to supplementation. Eur. J. Clin. Nutr. 2006, 60, 1009?015. 49. Blum, M.; Dolnikowski, G.; Syoum, E.; Harris, S.S.; Booth, S.L.; Peterson, J.; Saltzman, E.; Dawson-Hughes, B. Vitamin D3 in fat tissue. Endocrine 2008, 33, 90?4. 50. Zhao, L.J.; Zhou, Y.; Bu, F.; Travers-Gustafson, D.; Ye, A.; Xu, X.; Hamm, L.; Gorsage, D.M.; Fang, X.; Deng, H.W.; et al. Factors predicting vitamin D response variation in non-Hispanic white postmenopausal women. J. Clin. Endocrinol. Metab. 2012, 97, 2699?705. 51. Bell, N.H.; Shaw, S.; Turner, R.T. Evidence that calcium modulates circulating 25-hydroxyvitamin D in man. J. Bone Miner. Res.E.; Manson, J.E.; Giovannucci, E.L.; Moorthy, M.V.; Zhang, S.; Lee, I.-M.; Lin, J.H. Circulating vitamin D levels and risk of colorectal cancer in women. Cancer Prev. Res. 2015, doi:10.1158/1940-6207.CAPR-14-0470. 37. Canto-Costa, M.H.; Kunii, I.; Hauache, O.M. Body fat and cholecalciferol supplementation in elderly homebound individuals. Braz. J. Med. Biol. Res. 2006, 39, 91?8. 38. Saadi, H.F.; Dawodu, A.; Afandi, B.O.; Zayed, R.; Benedict, S.; Nagelkerke, N. Efficacy of daily and monthly high-dose calciferol in vitamin d eficient nulliparous and lactating women. Am. J. Clin. Nutr. 2007, 85, 1565?571. 39. Harris, S.S.; Dawson-Hughes, B. Plasma vitamin D and 25OHD responses of young and old men to supplementation with vitamin D3. J. Am. Coll. Nutr. 2002, 21, 357?62. 40. Barger-Lux, M.J.; Heaney, R.P.; Dowell, S.; Chen, T.C.; Holick, M.F. Vitamin D and its major metabolites: Serum levels after graded oral dosing in healthy men. Osteoporos. Int. 1998, 8, 222?30. 41. Nelson, M.L.; Blum, J.M.; Hollis, B.W.; Rosen, C.; Sullivan, S.S. Supplements of 20 g/d cholecalciferol optimized serum 25-hydroxyvitamin D concentrations in 80 of premenopausal women in winter. J. Nutr. 2009, 139, 540?46. 42. Goussous, R.; Song, L.; Dallal, G.E.; Dawson-Hughes, B. Lack of effect of calcium intake on the 25-hydroxyvitamin D response to oral vitamin D3. Clin. Endocrinol. Metab. 2005, 90, 707?11. 43. Bacon, C.J.; Gamble, G.D.; Horne, A.M.; Scott, M.A.; Reid, I.R. High-dose oral vitamin D3 supplementation in the elderly. Osteoporos. Int. 2009, 20, 1407?415. 44. Trang, H.M.; Cole, D.E.C.; Rubin, L.A.; Pierratos, A.; Siu, S.; Vieth, R. Evidence that vitamin D3 increases serum 25-hydroxyvitamin D more efficiently than does vitamin D2. Am. J. Clin. Nutr. 1998, 68, 854?58. 45. Zwart, S.R.; Mehta, S.K.; Ploutz-Snyder, R.; Bourbeau, Y.; Locke, J.P.; Pierson, D.L.; Smith, S.M. Response to vitamin D supplementation during antarctic winter is related to bmi, and supplementation can mitigate epstein-barr virus reactivation. J. Nutr. 2011, 141, 692?97. 46. Waterhouse, M.; Tran, B.; Armstrong, B.K.; Baxter, C.; Ebeling, P.R.; English, D.R.; Gebski, V.; Hill, C.; Kimlin, M.G.; Lucas, R.M.; et al. Environmental, personal, and genetic determinants of response to vitamin D supplementation in older adults. J. Clin. Endocrinol. Metab. 2014, 99, E1332 1340.Nutrients 2015,47. Ng, K.; Scott, J.B.; Drake, B.F.; Chan, A.T.; Hollis, B.W.; Chandler, P.D.; Bennett, G.G.; Giovannucci, E.L.; Gonzalez-Suarez, E.; Meyerhardt, J.A.; et al. Dose response to vitamin D supplementation in african americans: Results of a 4-arm, randomized, placebo-controlled trial. Am. J. Clin. Nutr. 2014, 99, 587?98. 48. DeLappe, E.; McGreevy, C.; ni Chadhain, N.; Grimes, H.; O’Brien, T.; Mulkerrin, E. Vitamin D insufficiency in older female community-dwelling acute hospital admissions and the response to supplementation. Eur. J. Clin. Nutr. 2006, 60, 1009?015. 49. Blum, M.; Dolnikowski, G.; Syoum, E.; Harris, S.S.; Booth, S.L.; Peterson, J.; Saltzman, E.; Dawson-Hughes, B. Vitamin D3 in fat tissue. Endocrine 2008, 33, 90?4. 50. Zhao, L.J.; Zhou, Y.; Bu, F.; Travers-Gustafson, D.; Ye, A.; Xu, X.; Hamm, L.; Gorsage, D.M.; Fang, X.; Deng, H.W.; et al. Factors predicting vitamin D response variation in non-Hispanic white postmenopausal women. J. Clin. Endocrinol. Metab. 2012, 97, 2699?705. 51. Bell, N.H.; Shaw, S.; Turner, R.T. Evidence that calcium modulates circulating 25-hydroxyvitamin D in man. J. Bone Miner. Res.
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