Pective evaluation of patients with Dimethylenastron diagnosis of gallbladder cancer between ,in a referral tertiary center. Results: We included sufferers ( females),using a median age of years. The median time of followup was months,having a mortality price of (n. The majority of sufferers PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/21046372 ( had history of cholelithiasis and have been diagnosed after cholecystectomy ( of these inside the context of acute cholecystitis). Essentially the most popular symptoms reported at admission had been abdominal pain (jaundice (and nauseavomiting The majority from the sufferers had slight cholestasis in laboratorial analysis. The neoplasms involved the gallbladder body or have been panvesicular in of instances. A nonspecific adenocarcinoma was essentially the most common diagnosis (with a median size of mm. At diagnosis, have been in an sophisticated stage (IIIIV). A surgery of curative intent was performed in of patients. The palliative approaches far more regularly used have been percutaneous drainage ( and chemorradiotherapy An endoscopic drainage was performed only in patients The mortality price at ,,and months was ,, and ,respectively. The presence of cholestasis (p.) and renal dysfunction (p.) at diagnosis correlated independently with early mortality. Conclusion: The gallbladder carcinoma was extra prevalent in ladies with advanced age,in many situations with prior cholelithiasis and in an advanced stage at diagnosis. Adenocarcinoma was probably the most prevalent histological type. Regardless of the higher price of surgical approaches for curative intent, didn’t survive beyond years just after the diagnosis. Disclosure of Interest: None declaredUnited European Gastroenterology Journal (S) Abstract number P Table . Hepatogastrostomy jejunostomy[HG(J)S] Quantity of the pts (AB) MaleFemale Imply age (variety) years Malignities Benign pathologies Indications (AB) Technical success price AB (Quantity of the sufferers)# Serious Complications:AB [ . ] (Bleeding in two casesone died,a single surgery; cholangitis and sepsis in one particular case; perforation in two situations (surgery required) Choledocho or cystoduodenostomy [CD(Cy)S] [ ] (Bile leak and biloma formation ( cm) requiring surgery in onecardiopulmonary arrest and death in one) CholecystoCholedochalRendezvous gastrostomy(CRV) jejunostomy[CG(J)S] Total [ ] (Surgery as a result of guidewire knotting in duodenum) [ A[ . ]] ( death,surgery,extended intensive care remain)P DIRECT RETROGRADE CHOLANGIOSCOPYDIRECTED BIOPSY IS SUPERIOR TO FLUOROSCOPYGUIDED BIOPSY TO DIFFERENTIATE INDETERMINATE BILIARY STRICTURE Within the DISTAL Frequent BILE DUCT,BUT NOT In the PORTA HEPATIS D. Walter,M. FriedrichRust,S. Zeuzem,J. Albert Medical Department ,University hospital Frankfurt,Frankfurt,Germany Speak to Email Address: dirk.walterkgu.de Introduction: Differentiation of indeterminate biliary stricture (IBS) by imaging modalities is restricted. Definite diagnosis is according to histopathology,but high rates of false unfavorable biopsies constrain the clinical management. Aims Procedures Aims: To investigate reason of higher false damaging results of intraductal biopsies obtained under fluoroscopic guidance in comparison to direct retrograde cholangioscopy (DRC). Procedures: All patients were retrospectively integrated who presented for diagnostic workup of IBS at our University hospital and who underwent an intraductal biopsy amongst and . Histopathological results of fluoroscopic vs DRCdirected intraductal biopsies had been compared with the golden typical of either postoperative histology or followup of at the very least one particular year and underlying illness of false unfavorable biopsies.