There was only one overlapping SNP of glucose and fructose-6-phosphate (F6P). In contrast, andSSC was only a ONO4059 hydrochloride single overlapping SNP of glucose and fructose-6-phosphate (F6P). In contrast, on SSC 1 on eight, 8, we indeed detected significant two traits two traits however the QTLs are positioned in distant 1 and we certainly detected considerable SNPs forSNPs for however the QTLs are situated in distant chromosomal regions. chromosomal regions.Figure 1. Overlapping SNPs at Sus scrofa chromosomes (SSC) 14, 17 and 18. PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21366659 GWAS procedures Figure 1. Overlapping SNPs at Sus scrofa chromosomes (SSC) 14, 17 and 18. GWAS procedures resultedvarying numbers ofof significantSNP (q 0.1) per trait. On some chromosomes you’ll find are resulted in in varying numbers substantial SNP (q 0.1) per trait. On some chromosomes there overlapping SNPs with meaning for two traits. Drip overlapping SNPs with which means for two traits. Drip loss measured inin Musculus longissimus dorsi (LD) loss measured Musculus longissimus dorsi (LD) 24 h post-mortem (p.m.); Glycerone-p = dihydroxyacetone phosphate; PGAM2 = phosphoglycerate 24 h post-mortem (p.m.); Glycerone-p = dihydroxyacetone phosphate; PGAM2 = phosphoglycerate mutase 2 (muscle); FBPase = fructose-1,6-bisphosphatase two; DG3P = D-glycerate-3-phosphate. mutase two (muscle); FBPase = fructose-1,6-bisphosphatase two; DG3P = D-glycerate-3-phosphate.The functional annotation on the 871 significantly connected SNPs revealed 1430 genes which are The functional annotation of your 871 and thereby are in linkage disequilibrium 1430 important situated in a distance of 1 Mb for the SNPssignificantly connected SNPs revealed to our genes that happen to be located in(Table four). 257 SNPs areto the SNPs and thereby are of a specificdisequilibrium to our important SNPs a distance of 1 Mb localized in an intron area in linkage gene. These genes, which are SNPs (Table four). 257 SNPs14, 17 and 18, may be crucial prospective candidate genes forgenes, which are mostly situated on SSC are localized in an intron area of a specific gene. These drip loss and linked metabolic traits and 18, could be critical prospective candidate genes for drip loss and mostly situated on SSC 14, 17and processes (Table four).associated metabolic traits and processes (Table 4).Table 4. Functional annotation of considerable SNPs connected with drip loss and metabolic traits.30 148 four 65 31 48 70 15 12 375 13 367 252Table 4. Functional annotation of6significant SNPs 10 13 related with drip loss and metabolic traits. SSC 1 1 two three 4 7 8 14 16 17Genes1 SNP83195 14 -4 54275 63197 257871 1 27 two 3097 3 -1 1533 215 -13 227 12 1055 13 four 6 7 8 16 17 18 SSC two number of genes that are positioned in a distance of 1 Mb to 367 important 30 four 65 31 48 70 15 12 375 13 252 1430 Genes two 1 Sus scrofa148 chromosomes; the 27 3097 GWAS; 3 quantity of intronic SNPs in relation55the total quantity of important SNPs 257871 1533 215 -13 227 12 83195 -4 54275 63197 SNP 3 SNPs revealed by -1 toSus scrofa chromosomes; 2 variety of genes that overlapping SNPs). per chromosome (without having double counting of are positioned inside a distance of 1 Mb to the important SNPs revealed by GWAS; three number of intronic SNPs in relation for the total variety of significant SNPs per chromosome (without having double counting of overlapping SNPs).Int. J. Mol. Sci. 2016, 17,7 ofInt. J. Mol. Sci. 2016, 17,7 ofFor the identification of prospective candidate genes, we concentrated on the most significant QTL For the identification of possible candidate genes, we concent.