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have been not significant, most likely due to the small sample size, the low recurrence rate, and also the short follow-up period following anticoagulation suspension.Results: A total of 80 individuals were enrolled within this study. There had been 48 patients (60 ) with high-risk mortality PE and 32 patients (40 ) classified as intermediate danger mortality PE. Seven patients (8.75 ) had died at the time of hospital discharge and all of those were classified in the high-risk mortality group. All 73 sufferers who have been alive at discharge had been alive soon after three months adhere to up. There have been 1 patient (1.25 ) of main bleeding and 7 (eight.75 ) of minor bleeding. Conclusions: Accelerated regimen with 0.6mg per kilogram of body weight over 15 minutes of alteplase was initiallyeffective and safe on Vietnamese patients with acute pulmonary embolism after 3 months adhere to up. Table 1: The characteristic of dead case Patient Sex Age LOS Cardiac arrest resulting from PE Detail No 1. Female 54 8 Yes Comatose with multiorgan failure following cardiac arrest No two. Female 94 18 No Initially enhanced but develiped ventilator connected pneumonia and septic shock at day three. No 3. Male 69 1 No Hemodynamic were not enhanced. Sufferers delegate didn’t agree to thrombectomy (patient had pre-existing colon cancer). No 4. Female 75 two Yes Comatose soon after cardiac arrest in spite of returning to spontaneous circulation No five. Male 59 1 Yes Refractory shock No 6. Female 63 1 Yes Cardiac arrest soon after diagnosis with no ROSC No 7. Male 74 1 No Lung cancer was located 1 day after applying alteplase. Hemodynamic had been not improved and therapy withdrawnPB1278|The Accelerated Regimen of Low Dose Recombinant Tissue-type Plasminogen for the Therapy of Acute Pulmonary Embolism: A Case Series from Vietnam B.H. Hoang1; G.P. Do2; D.L. Le3; T.H.T. Bui4; N.T. Bui5; M.Q. Nguyen3; D.A. Nguyen4; M.M Dinh6; L.H. NguyenTable two: In-hospital adverse CB1 Agonist Purity & Documentation events High- risk mortality PE group n = 48 Intermediate-high risk PE group n = 32 Total N = 80 Probability value Age 60.six 18.84 63.1 18.71 61.6 18.71 0.42 (sign test) Length of stay 9.7 6.76 7.9 4.91 8.9 5.99 0.25 (sign test) Inhospital bleeding complications Big intracranial bleeding 0 0 Main bleeding or needing a blood transfusion 0 1 (blood loss as a consequence of menstrual bleeding) Minor bleeding (bleeding on account of urethral/stomach catheter placement, bleeding tooth) two (4.two ) five (15.6 ) 0.086 (Fisher’s precise test) Additionally, there had been 2/80 (two.5 ) patients who created chronic thromboembolic pulmonary hypertension at 3 months follow up.Hanoi Healthcare University Hospital Hanoi Medical University, Hanoi,Vietnam; 2Hanoi Healthcare University Hospital, Hanoi, Vietnam; 3Thu Duc District Hospital, Ho Chi Minh City, Vietnam; 4Hanoi Medical University, Hanoi, Vietnam; 5Thu Duc District Hospital – Pham Ngoc Thach Medical College, Ho Chi Minh City, Vietnam; 6Royal Prince Alfred Hospital- The University of Sydney, Sydney Healthcare School, Sydney, AustraliaPB1279|Efficacy and Safety Calcium Channel Inhibitor manufacturer Comparison of DOACs versus Background: Pulmonary reperfusion in acute pulmonary embolism (PE) by utilizing a fixed complete dose regimen of 100 mg of recombinant tissue-type plasminogen activator (rt-PA) more than two hours or an accelerated low-dose rt-PAregimen has not only been controversial in Vietnam. Aims: To describe the outcomes of an accelerated low-dose rt-PA regimen for the treatment of high to intermediate mortality risk PE in Vietnamese individuals. Methods: This was a case series study, the PE patients of high to intermediate

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