G these with a high soil pH and upland cultivation.ACKNOWLEDGMENTSWe

G those with a high soil pH and upland cultivation.ACKNOWLEDGMENTSWe thank Dr. Mitsuru Abo (The University of Tokyo) for technical support for ICP-AES analysis, Dr. Kyoko Higuchi and Dr. Teppei Maruyama (Tokyo University of Agriculture) for help in rice cultivation. We also thank Ms. Reiko Nakanishi Itai and Dr. Motofumi Suzuki (The University of Tokyo) for technical suggestions regarding Northern blot evaluation. We thank Dr. Fumiyuki Goto (CRIEPI, Japan) for providing soybean ferritin antibody, and Dr. Toshihiro Yoshihara (CRIEPI, Japan) and Dr. Fumio Takaiwa (NIAS, Japan) for supplying OsGlb1 promoter, OsGluB1 promoter, and SoyferH2 gene. This perform was supported by the Harvest Plus project, Core Investigation for Evolutional Science and Technologies (CREST), and also the Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan.SUPPLEMENTARY MATERIALThe Supplementary Material for this short article is usually located on-line at: http://www.frontiersin.org/Plant_Physiology/10.3389/ fpls.2013.00132/abstractHiei, Y., Ohta, S., Komari, T., and Kumashiro, T.Astragaloside IV Inhibitor (1994). Effective transformation of rice (Oryza sativa L.) mediated by Agrobacterium and sequence analysis of your boundaries with the T-DNA. Plant J. 6, 27182. Higuchi, K., Suzuki, K., Nakanishi, H., Yamaguchi, H., Nishizawa, N. K., and Mori, S. (1999). Cloning of nicotianamine synthase genes, novel genes involved in the biosynthesis of phytosiderophores.Ganoderic acid A site Plant Physiol. 119, 47179. Higuchi, K., Watanabe, S., Takahashi, M., Kawasaki, S., Nakanishi, H., Nishizawa, N. K., et al. (2001). Nicotianamine synthase gene expression differs in barley and rice below Fe-deficient conditions. Plant J. 25, 15967. Inoue, H., Higuchi, K., Takahashi, M., Nakanishi, H., Mori, S., and Nishizawa, N. K. (2003). 3 rice nicotianamine synthase genes, OsNAS1, OsNAS2, and OsNAS3 are expressed in cells involved in longdistance transport of iron and differentially regulated by iron. Plant J. 36, 36681. Inoue, H., Kobayashi, T., Nozoye, T., Takahashi, M., Kakei, Y.PMID:36014399 , Suzuki, K., et al. (2009). Rice OsYSL15 is an iron-regulated iron(III)deoxymugineic acid transporter expressed within the roots and is crucial for iron uptake in early development of your seedlings. J. Biol. Chem. 284, 3470479. Inoue, H., Takahashi, M., Kobayashi, T., Suzuki, M., Nakanishi, H., Mori, S., et al. (2008). Identification and localization on the rice nicotianamine aminotransferase gene OsNAAT1 expression suggests the
Post pubs.acs.org/bcTerms of UseDesign, Synthesis, and Structure-Activity Relationship Studies of Fluorescent Inhibitors of Cycloxygenase2 as Targeted Optical Imaging AgentsMd. Jashim Uddin, Brenda C. Crews, Kebreab Ghebreselasie, and Lawrence J. Marnett*A. B. Hancock, Jr., Memorial Laboratory for Cancer Analysis, Department of Biochemistry, Chemistry and Pharmacology, Vanderbilt Institute of Chemical Biology, Center for Molecular Toxicology and Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-0146, United StatesS * Supporting InformationABSTRACT: Cycloxygenase-2 (COX-2) is definitely an eye-catching target for molecular imaging because it is an inducible enzyme that’s expressed in response to inflammatory and proliferative stimuli. Recently, we reported that conjugation of indomethacin with carboxy-X-rhodamine dyes benefits inside the formation of powerful, targeted, optical imaging agents in a position to detect COX-2 in inflammatory tissues and premalignant and malignant tumors (Uddin et al. Cancer Res. 2010.