Product Name :
PARP14 inhibitor H10
Description:
PARP14 inhibitor H10, compound H 10, is a selective inhibitor against PARP14 (IC50=490 nM), over other PARPs (≈24 fold over PARP1). PARP14 inhibitor H10 induces caspase-3/7-mediated cell apoptosis.
CAS:
2084811-68-5
Molecular Weight:
557.58
Formula:
C24H27N7O7S
Chemical Name:
3-(2-[4-(2-3-[(3-carbamoylphenyl)carbamoyl]propanamidoethyl)-1H-1, 2, 3-triazol-1-yl]ethylsulfamoyl)benzoic acid
Smiles :
NC(=O)C1=CC(=CC=C1)NC(=O)CCC(=O)NCCC1=CN(CCNS(=O)(=O)C2=CC(=CC=C2)C(O)=O)N=N1
InChiKey:
MUOMSHSMJCWQFH-UHFFFAOYSA-N
InChi :
InChI=1S/C24H27N7O7S/c25-23(34)16-3-1-5-18(13-16)28-22(33)8-7-21(32)26-10-9-19-15-31(30-29-19)12-11-27-39(37,38)20-6-2-4-17(14-20)24(35)36/h1-6,13-15,27H,7-12H2,(H2,25,34)(H,26,32)(H,28,33)(H,35,36)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
PARP14 inhibitor H10, compound H 10, is a selective inhibitor against PARP14 (IC50=490 nM), over other PARPs (≈24 fold over PARP1). PARP14 inhibitor H10 induces caspase-3/7-mediated cell apoptosis.|Product information|CAS Number: 2084811-68-5|Molecular Weight: 557.58|Formula: C24H27N7O7S|Chemical Name: 3-(2-[4-(2-3-[(3-carbamoylphenyl)carbamoyl]propanamidoethyl)-1H-1, 2, 3-triazol-1-yl]ethylsulfamoyl)benzoic acid|Smiles: NC(=O)C1=CC(=CC=C1)NC(=O)CCC(=O)NCCC1=CN(CCNS(=O)(=O)C2=CC(=CC=C2)C(O)=O)N=N1|InChiKey: MUOMSHSMJCWQFH-UHFFFAOYSA-N|InChi: InChI=1S/C24H27N7O7S/c25-23(34)16-3-1-5-18(13-16)28-22(33)8-7-21(32)26-10-9-19-15-31(30-29-19)12-11-27-39(37,38)20-6-2-4-17(14-20)24(35)36/h1-6,13-15,27H,7-12H2,(H2,25,34)(H,26,32)(H,28,33)(H,35,36)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 62.Voclosporin Autophagy 5 mg/mL (112.Belzutifan Epigenetics 09 mM; Need ultrasonic)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:32350699 |Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Peng B, et al. Small Molecule Microarray Based Discovery of PARP14 Inhibitors. Angew Chem Int Ed Engl. 2017 Jan 2;56(1):248-253.Products are for research use only. Not for human use.|
