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Product Name :
(Rac)-PT2399

Description:
(Rac)-PT2399 (Compound 10e), the racemate of PT2399, acts as a potent and specific hypoxia-inducible factor 2a (HIF-2α) inhibitor with an IC50 of 0.01 μM.

CAS:
1672662-07-5

Molecular Weight:
419.32

Formula:
C17H10F5NO4S

Chemical Name:
3-[(7-difluoromethanesulfonyl-2,2-difluoro-1-hydroxy-2,3-dihydro-1H-inden-4-yl)oxy]-5-fluorobenzonitrile

Smiles :
N#CC1=CC(F)=CC(=C1)OC1=CC=C(C2C(O)C(F)(F)CC=21)S(=O)(=O)C(F)F

InChiKey:
MXUSGDMIHGLCNC-UHFFFAOYSA-N

InChi :
InChI=1S/C17H10F5NO4S/c18-9-3-8(7-23)4-10(5-9)27-12-1-2-13(28(25,26)16(19)20)14-11(12)6-17(21,22)15(14)24/h1-5,15-16,24H,6H2

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
(Rac)-PT2399 (Compound 10e), the racemate of PT2399, acts as a potent and specific hypoxia-inducible factor 2a (HIF-2α) inhibitor with an IC50 of 0.01 μM.|Product information|CAS Number: 1672662-07-5|Molecular Weight: 419.32|Formula: C17H10F5NO4S|Chemical Name: 3-[(7-difluoromethanesulfonyl-2,2-difluoro-1-hydroxy-2,3-dihydro-1H-inden-4-yl)oxy]-5-fluorobenzonitrile|Smiles: N#CC1=CC(F)=CC(=C1)OC1=CC=C(C2C(O)C(F)(F)CC=21)S(=O)(=O)C(F)F|InChiKey: MXUSGDMIHGLCNC-UHFFFAOYSA-N|InChi: InChI=1S/C17H10F5NO4S/c18-9-3-8(7-23)4-10(5-9)27-12-1-2-13(28(25,26)16(19)20)14-11(12)6-17(21,22)15(14)24/h1-5,15-16,24H,6H2|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 120 mg/mL (286.DREADD agonist 21 manufacturer 18 mM; Need ultrasonic).Sotigalimab Epigenetics |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:32924753 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|

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