Product Name :
Climbazole
Description:
Climbazole (BAY-e 6975) is a potent antifungal agent. Climbazole also is a potent inducer of rat hepatic cytochrome P450.
CAS:
38083-17-9
Molecular Weight:
292.76
Formula:
C15H17ClN2O2
Chemical Name:
1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one
Smiles :
CC(C)(C)C(=O)C(OC1C=CC(Cl)=CC=1)N1C=NC=C1
InChiKey:
OWEGWHBOCFMBLP-UHFFFAOYSA-N
InChi :
InChI=1S/C15H17ClN2O2/c1-15(2,3)13(19)14(18-9-8-17-10-18)20-12-6-4-11(16)5-7-12/h4-10,14H,1-3H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Climbazole (BAY-e 6975) is a potent antifungal agent. Climbazole also is a potent inducer of rat hepatic cytochrome P450.|Product information|CAS Number: 38083-17-9|Molecular Weight: 292.76|Formula: C15H17ClN2O2|Chemical Name: 1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one|Smiles: CC(C)(C)C(=O)C(OC1C=CC(Cl)=CC=1)N1C=NC=C1|InChiKey: OWEGWHBOCFMBLP-UHFFFAOYSA-N|InChi: InChI=1S/C15H17ClN2O2/c1-15(2,3)13(19)14(18-9-8-17-10-18)20-12-6-4-11(16)5-7-12/h4-10,14H,1-3H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : ≥ 47 mg/mL (160.54 mM).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Daptomycin Purity & Documentation |Shelf Life: ≥12 months if stored properly.PA-9 PACAP Receptor |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:33189710 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Climbazole (20 µM; 48 hours) significantly decreases exosome secretion in aggressive prostate cancer (PCa) cells. Climbazole (20 µM) significantly inhibits the protein concentration of Alix, and Rab27a but not nSMase2. Climbazole is a potent inhibitor of exosome biogenesis and/or secretion.|Products are for research use only. Not for human use.|
