Product Name :
Cloxiquine
Description:
Cloxiquine (5-Chloro-8-quinolinol) is an antibacterial, antifungal and antiamoebic agent. Cloxiquine can be used for the research of tuberculosis and dermatoses. Cloxiquine suppresses the growth and metastasis of melanoma cells through activation of PPARγ.
CAS:
130-16-5
Molecular Weight:
179.60
Formula:
C9H6ClNO
Chemical Name:
5-chloroquinolin-8-ol
Smiles :
OC1C=CC(Cl)=C2C=CC=NC2=1
InChiKey:
CTQMJYWDVABFRZ-UHFFFAOYSA-N
InChi :
InChI=1S/C9H6ClNO/c10-7-3-4-8(12)9-6(7)2-1-5-11-9/h1-5,12H
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Cloxiquine (5-Chloro-8-quinolinol) is an antibacterial, antifungal and antiamoebic agent. Cloxiquine can be used for the research of tuberculosis and dermatoses. Cloxiquine suppresses the growth and metastasis of melanoma cells through activation of PPARγ.|Product information|CAS Number: 130-16-5|Molecular Weight: 179.60|Formula: C9H6ClNO|Chemical Name: 5-chloroquinolin-8-ol|Smiles: OC1C=CC(Cl)=C2C=CC=NC2=1|InChiKey: CTQMJYWDVABFRZ-UHFFFAOYSA-N|InChi: InChI=1S/C9H6ClNO/c10-7-3-4-8(12)9-6(7)2-1-5-11-9/h1-5,12H|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 100 mg/mL (556.79 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.Maftivimab custom synthesis |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Cloxiquine (cloxyquin) exhibits antituberculosis activities, with MICs ranging from 0.PDGF-BB Protein, Human Biological Activity 062 to 0.PMID:33272102 25 μg/mL against 9 standard strains and 150 Mycobacterium tuberculosis. Cloxiquine (0.5-10 μM; 24 h) suppresses both B16F10 and A375 cell growth in a dose-dependent manner. Cloxiquine (0.5-10 μM; 24 h) inhibits the migration of B16F10 and A375 cells. Cloxiquine (0.5-2.5 μM; 24 h) suppresses glycolysis in B16F10 cells.|In Vivo:|Cloxiquine (5-25 mg/kg; i.p. daily for 8 d) suppresses tumor growth in a mouse B16F10 melanoma xenograft model. Cloxiquine (5-25 mg/kg; i.p. daily for 14 d) suppresses tumor metastasis in mouse B16F10 melanoma lung metastatic model.|Products are for research use only. Not for human use.|
