Product Name :
Rabbit anti-SPRR1B Polyclonal Antibody(C-term)
Synonym :
Cornifin-B; 149 kDa pancornulin; Small proline-rich protein IB; SPR-IB; SPRR1B
Host :
Rabbit
Species Reactivity:
Human
Specificity :
This SPRR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-89 amino acids from the C-terminal region of human SPRR1B.
Predicted Reactivity:
Applications :
WB~~1:1000IHC-P~~1:50~100
Immunogen:
Concentration :
Purification :
Clonality:
Polyclonal Antibody
Storage Temp.:
Maintain refrigerated at 2-8 ° C for up to 2 weeksFor long time storage store at -20 ° C in small aliquots to prevent free that cycles
Research areas :
SPRR1B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Background :
Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross- linkage.
UniProt :
P22528
Additional information:
Product Details FAQ Citations(1) Video Pictures Documents |Overview |Description Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab) |Synonym Cornifin-B; 149 kDa pancornulin; Small proline-rich protein IB; SPR-IB; SPRR1B |Host Rabbit |Specificity This SPRR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-89 amino acids from the C-terminal region of human SPRR1B. |Species Reactivity Human |Applications WB~~1:1000IHC-P~~1:50~100 |Properties |Clonality Polyclonal Antibody |Isotype Rabbit Ig |Storage Temp. Maintain refrigerated at 2-8 ° C for up to 2 weeksFor long time storage store at -20 ° C in small aliquots to prevent free that cycles |Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |Research areas SPRR1B Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |Target |Background Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross- linkage. |Cellular localization Cytoplasm. |UniProt P22528 |References |References Stemmler,S., et.al., Int. J. Immunogenet. 36 (4), 217-222 (2009)Kainu,K., et.al., Exp. Dermatol. 18 (2), 109-115 (2009) |Tips:This product is for research use only. Not for use in diagnostic prodcedures.
Rabbit anti-SPRR1B Polyclonal Antibody(C-term)
Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.Related websites: https://www.medchemexpress.com/antibodies.html
284028-89-3 Technical Information 2495096-26-7 manufacturer PMID:29939569 MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use. We have professionally experienced and friendly staff to meet your needs. We are a competent and trustworthy partner for your research and scientific projects.Related websites: https://www.medchemexpress.com
