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Product Name :
PLA-PEG-COOH, PLA 2k & PEG 2k

Classification :
PEG Copolymers / PLA-PEG-COOH, PLA 2k & PEG 2k

Description :
Acid and NHS ester functionalized PEG-PLA is a useful reagent to prepare core-shell nanoparticles with an amine-reactive maleimide for conjugation with peptide or proteins bearing free amine. PEG-PLA is an amphiphilic AB diblock copolymer consisting of a hydrophilic block polyethylene glycol (PEG) or polyethylene oxide (PEO) and a hydrophobic block polylactic acid or polylactide (PLA). The PEG polymer is capped a methyl ether group, and the hydrophobic block terminates with a hydroxyl group. PEGylated copolymers with biodegradable and biocompatible polyester segments can be used to prepare core-shell micelles, nanoparticles and microspheres.

Properties:

References:
1) Biodegradable long-circulating polymeric nanospheres. Science 1994;363:1600–3, Text.2) Preparation, characterization and properties of polylactide (PLA) – poly(ethylene glycol) (PEG) copolymers: a potential drug carrier. J Appl Polym Sci 1990;39: 1–9, Text.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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