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Product name: Begacestat- GSI 953
Chemical name: (S)-5-chl or o-N-(4,4,4-triflu or o-1-hydroxy-3-(triflu or omethyl)butan-2-yl)thiophene-2-sulfonamideWeb Site click
MF: C9H8ClF6NO3S2
MW: 391.74
C AS NO: 1201595 Product: Pizotifen (malate)
Purity: 99%
Soluble: Soluble in DMSOEGFR Inhibitor s
Description: potent and selective γ-secret ASe Inhibitor (γ-secrat ASe Inhibitor ,GSI);Capable of reducingbothAβ40 and Aβ42productionina cell linestablyexpressinghumanrecombinantAPP(EC50 values of 14.8 and 12.4nMf or Aβ40 and Aβ40respectively).Begacestatw AS found to have>16-foldselectivityinvitPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22328189

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